Publications
KEY PAPERS
1: Hsia CJC, Messerli SM, Miskimins WK. Can Anti-Metastatic Albumin-based
Superoxide Dismutase Mimetic Serve as a "Moonshot" Drug for Treatment for Brain
Tumors - From Medulloblastoma to Glioblastoma? Cell Biochem Biophys. 2019
Jun;77(2):121-122. doi: 10.1007/s12013-019-00869-2. Epub 2019 May 15. PubMed
PMID: 31093886.
2: Messerli SM, Schaefer AM, Zhuang Y, Soltys BJ, Keime N, Jin J, Ma L, Hsia CJC,
Miskimins WK. Use of Antimetastatic SOD3-Mimetic Albumin as a Primer in Triple
Negative Breast Cancer. J Oncol. 2019 Feb 28;2019:3253696. doi:
10.1155/2019/3253696. eCollection 2019. PubMed PMID: 30941174; PubMed Central
PMCID: PMC6420975.
3: Hsia CJC, Miskimins WK. Can Macromolecular Nitroxide Work as Extracellular
Superoxide Dismutase Mimetic in Cancer and Stroke Therapy? Cell Biochem Biophys.
2018 Dec;76(4):443-444. doi: 10.1007/s12013-018-0853-6. Epub 2018 Sep 6. PubMed
PMID: 30191451.
4: Cao S, Zhang J, Ma L, Hsia CJC, Koehler RC. Transfusion of Polynitroxylated
Pegylated Hemoglobin Stabilizes Pial Arterial Dilation and Decreases Infarct
Volume After Transient Middle Cerebral Artery Occlusion. J Am Heart Assoc. 2017
Sep 12;6(9). pii: e006505. doi: 10.1161/JAHA.117.006505. PubMed PMID: 28899897;
PubMed Central PMCID: PMC5634295.
5: Brockman EC, Jackson TC, Dixon CE, Bayɪr H, Clark RS, Vagni V, Feldman K, Byrd
C, Ma L, Hsia C, Kochanek PM. Polynitroxylated Pegylated Hemoglobin-A Novel,
Small Volume Therapeutic for Traumatic Brain Injury Resuscitation: Comparison to
Whole Blood and Dose Response Evaluation. J Neurotrauma. 2017 Apr
1;34(7):1337-1350. doi: 10.1089/neu.2016.4656. Epub 2017 Jan 13. PubMed PMID:
27869558; PubMed Central PMCID: PMC5385578.
6: Hsia CJ. Fast track approval of therapeutic blood substitutes. Artif Organs.
2014 Mar;38(3):179-81. doi: 10.1111/aor.12281. PubMed PMID: 24606130.
7: Brockman EC, Bayır H, Blasiole B, Shein SL, Fink EL, Dixon C, Clark RS, Vagni
VA, Ma L, Hsia CJ, Tisherman SA, Kochanek PM. Polynitroxylated-pegylated
hemoglobin attenuates fluid requirements and brain edema in combined traumatic
brain injury plus hemorrhagic shock in mice. J Cereb Blood Flow Metab. 2013
Sep;33(9):1457-64. doi: 10.1038/jcbfm.2013.104. Epub 2013 Jun 26. PubMed PMID:
23801241; PubMed Central PMCID: PMC3764379.
8: Manole MD, Kochanek PM, Foley LM, Hitchens TK, Bayır H, Alexander H, Garman R,
Ma L, Hsia CJ, Ho C, Clark RS. Polynitroxyl albumin and albumin therapy after
pediatric asphyxial cardiac arrest: effects on cerebral blood flow and neurologic
outcome. J Cereb Blood Flow Metab. 2012 Mar;32(3):560-9. doi:
10.1038/jcbfm.2011.165. Epub 2011 Nov 30. PubMed PMID: 22126915; PubMed Central
PMCID: PMC3293121.
9: Hsia CJ, Ma L. A hemoglobin-based multifunctional therapeutic:
polynitroxylated pegylated hemoglobin. Artif Organs. 2012 Feb;36(2):215-20. doi:
10.1111/j.1525-1594.2011.01307.x. Epub 2011 Sep 28. PubMed PMID: 21955160; PubMed
Central PMCID: PMC3653627.
10: Shellington DK, Du L, Wu X, Exo J, Vagni V, Ma L, Janesko-Feldman K, Clark
RS, Bayir H, Dixon CE, Jenkins LW, Hsia CJ, Kochanek PM. Polynitroxylated
pegylated hemoglobin: a novel neuroprotective hemoglobin for acute volume-limited
fluid resuscitation after combined traumatic brain injury and hemorrhagic
hypotension in mice. Crit Care Med. 2011 Mar;39(3):494-505. doi:
10.1097/CCM.0b013e318206b1fa. PubMed PMID: 21169820; PubMed Central PMCID:
PMC3425360.
11: Exo JL, Shellington DK, Bayir H, Vagni VA, Janesco-Feldman K, Ma L, Hsia CJ,
Clark RS, Jenkins LW, Dixon CE, Kochanek PM. Resuscitation of traumatic brain
injury and hemorrhagic shock with polynitroxylated albumin, hextend, hypertonic
saline, and lactated Ringer's: Effects on acute hemodynamics, survival, and
neuronal death in mice. J Neurotrauma. 2009 Dec;26(12):2403-8. doi:
10.1089/neu.2009.0980. PubMed PMID: 19691424; PubMed Central PMCID: PMC2864460.
12: Kaul DK, Liu XD, Zhang X, Ma L, Hsia CJ, Nagel RL. Inhibition of sickle red
cell adhesion and vasoocclusion in the microcirculation by antioxidants. Am J
Physiol Heart Circ Physiol. 2006 Jul;291(1):H167-75. Epub 2006 Jan 27. PubMed
PMID: 16443674.
13: Mahaseth H, Vercellotti GM, Welch TE, Bowlin PR, Sonbol KM, Hsia CJ, Li M,
Bischof JC, Hebbel RP, Belcher JD. Polynitroxyl albumin inhibits inflammation and
vasoocclusion in transgenic sickle mice. J Lab Clin Med. 2005 Apr;145(4):204-11.
PubMed PMID: 15962839.